ABSTRACT
Literature on COVID-19-associated pulmonary mucormycosis (CAPM) is sparse. Pulmonary artery pseudoaneurysm (PAP) is an uncommon complication of pulmonary mucormycosis (PM), and rarely reported in CAPM. Herein, we report five cases of CAPM with PAP managed at our center and perform a systematic review of the literature. We diagnosed PM in those with clinico-radiological suspicion and confirmed it by microbiology or histopathology. We encountered five cases of CAPM with PAP (size ranged from 1 × 0.8 cm to ~ 4.9 × 4.8 cm). All subjects had diabetes and were aged 55-62 years (75% men). In two cases, COVID-19 and mucormycosis were diagnosed simultaneously, while in three others, COVID-19 preceded PM. One subject who underwent surgery survived, while all others died (80% mortality). From our systematic review, we identified one additional case of CAPM with PAP in a transplant recipient. CAPM with PAP is rare with high mortality. Early diagnosis and multimodality management are imperative to improve outcomes.
Subject(s)
Aneurysm, False , COVID-19 , Mucormycosis , Aneurysm, False/diagnosis , Aneurysm, False/etiology , Female , Humans , Male , Mucormycosis/complications , Mucormycosis/diagnosis , Pulmonary Artery/diagnostic imaging , SARS-CoV-2Subject(s)
Aneurysm, False/diagnosis , Bronchial Arteries/pathology , Hemoptysis/diagnosis , Aneurysm, False/therapy , Computed Tomography Angiography/methods , Cone-Beam Computed Tomography/methods , Contrast Media/administration & dosage , Cough/diagnosis , Cough/etiology , Embolization, Therapeutic/methods , Emergency Service, Hospital , Endovascular Procedures/instrumentation , Hemoptysis/etiology , Humans , Male , Middle Aged , Treatment OutcomeABSTRACT
COVID-19 pandemic triggered in many patients the fear to go to the emergency rooms in order to avoid a possible infection. This phenomenon caused a significant reduction in acute coronary syndrome-related interventional procedures with a subsequent increase in critical hospitalizations and post-infarction mechanical complications. A case series of cardiac ruptures during the COVID-19 lockdown and the surgical treatment of a huge post-ischemic cardiac pseudoaneurysm complicated by a "contained" free wall rupture are presented.